Luteolin 5-O-β-L-galactoside from Dracocephalum nutans
نویسندگان
چکیده
منابع مشابه
Bioactive constituents from Dracocephalum subcapitatum (O. Kuntze) Lipsky.
From an EtOAc extract of Dracocephalum subcapitatum, five flavonoids, calycopterin, xanthomicrol, isokaempferide, luteolin and apigenin, together with five terpenoids, oleanolic acid, ursolic acid, geranial, neral and limonene-10-al, were isolated. Among them, citral and limonene-10-al were the most effective components against epimastigotes of Trypanosoma cruzi, the parasitic agent of Chagas d...
متن کاملPhytochemical screening and evaluation of antioxidant activities of Dracocephalum kotschyi and determination of its luteolin content
OBJECTIVE Dracocephalum kotschyi (Lamiaceae family) has been used in traditional medicine for stomach and liver disorders, headache and congestion. In the present study, we have investigated phytochemical properties and antioxidant activities of dichloromethane, ethyl acetate and methanol extracts of D.kotschyi. MATERIAL AND METHODS Antioxidant activities of extracts were evaluated using the ...
متن کاملEffects of luteolin 5-O-beta-rutinoside in streptozotocin-induced diabetic rats.
We have investigated the antidiabetic activity of luteolin 5-rutinoside in streptozotocin(STZ)-induced diabetic rats. Treatment for 20 days with 2 mg/kg increased both pancreatic insulin and DNA content. When both luteolin 5-rutinoside (2 mg/kg) and glibenclamide (1 mg/kg) were administered concurrently to STZ-diabetic rats, a marked antidiabetic activity was achieved. This effect was evidenced...
متن کاملThe Flavonoid Luteolin, but Not Luteolin-7-O-Glucoside, Prevents a Transthyretin Mediated Toxic Response
Transthyretin (TTR) is a homotetrameric plasma protein with amyloidogenic properties that has been linked to the development of familial amyloidotic polyneuropathy (FAP), familial amyloidotic cardiomyopathy, and senile systemic amyloidosis. The in vivo role of TTR is associated with transport of thyroxine hormone T4 and retinol-binding protein. Loss of the tetrameric integrity of TTR is a rate-...
متن کاملSignificance of β-Galactoside α2,6 Sialyltranferase 1 in Cancers.
Altered glycosylation is a common feature of cancer cells. It takes a variety of forms, which includes loss of expression or excessive expression of some structures, the accumulation of precursors, the appearance of novel structures, etc. Notably, these changes in glycan structure do not occur as a random consequence of disorder biology. Only a limited subset of oligosaccharides is found freque...
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ژورنال
عنوان ژورنال: Chemistry of Natural Compounds
سال: 1977
ISSN: 0009-3130,1573-8388
DOI: 10.1007/bf00565850